Whether you’re starting your morning off right or planning a fun party, these cannabis-infused watermelon shooter shots are nutritious, delicious, quick, and easy to make, complete with various cannabis infusion options.

Why You Will Love This Guide

Shooters, aka wellness shots, are small amounts of liquid that are taken as a shot.

The goal is to consume a lot of nutrients in a small volume while reaping the benefits of the nutritious ingredients.

Members of my Well With Cannabis Community love to consume cannabis this way because it eliminates the taste, is easy to do, and provides long-lasting benefits.

In just a small 2-ounce shot, you will get the benefits of watermelon, apple cider vinegar, freshly ground spices, and of course, cannabis.

Read on to get the full recipe along with helpful tips, tricks, and fun facts about watermelon nutrition.

Ingredient Notes

  • Watermelon puree – learn how to make watermelon puree below
  • Apple cider vinegar – for taste and health benefits
  • Honey – you can use cannabis honey if desired
  • Pumpkin pie spice – for the taste and benefits of each spice
  • Cannabis tincture – or your choice of an alternate infusion option below

Note: a complete list of ingredients with amounts and printable instructions is located in the recipe card below.

How to Make Watermelon Puree

Watermelon puree is the staple of this recipe, and it couldn’t be easier to make with a blender at home.

To make watermelon puree, simply add freshly diced watermelon pieces, without the rind, to a blender and blend on high until smooth.

Due to the high water content and low fiber content of watermelon, it is easily broken down and will turn into a puree/juice within 30-60 seconds. 

Alternate Infusion Options

As with all things cannabis, there are many different ways to infuse something.

For this recipe, I recommend infusing these wellness shots with an alcohol-based cannabis tincture, but I have other options outlined below as well.

Cannabis Tincture

My favorite way to infuse these wellness shots is to add a bit of a cannabis tincture.

You will want to prepare either the Green Dragon tincture or the QWET Freezer Golden Dragon tincture before getting started.

You could also try a THCA tincture or CBDA tincture, depending on the effect you’re looking for.

If you do not want a lot of alcohol in this wellness shot, be sure to evaporate a majority of the alcohol from the tincture first.

Cannabis Oil

While not my favorite way, you can infuse these shots with cannabis oil. The texture shouldn’t be a problem, as they are quickly drunk as a shot.

I don’t think solid infusions like coconut oil or cannabutter would work well in this recipe; it should be a liquid cannabis oil to maintain the best consistency.

Make This A Watermelon Vodka Cocktail

During times of good health, alcohol can be a mindful addition to any diet to enhance a social experience.

Instead of consuming a mixer like soda, which contains empty calories, watermelon juice is nutrient-dense and tastes delicious.

To Make a Watermelon Vodka Drink

  • Make this recipe according to the recipe directions.
  • Combine 2-ounces of the prepared watermelon shooter with 2-ounces of seltzer and 1-ounce of liquid of choice: I recommend a clear liquor like vodka or rum.
  • Get more delicious cannabis drink ideas from my Cannabis Cocktail Cookbook

The Health Benefits of Watermelon

Packed with important nutrients, the beautiful pink color signals the presence of powerful phytonutrients like carotenoids, specifically lycopene.

Typically, we associate lycopene with the health benefits of tomatoes, but recent studies have proven that red-fleshed watermelon is, in fact, a more concentrated source of lycopene, and that the lycopene may be more bioavailable in the body. 

Lycopene, vitamin C, and many other flavonoids found in watermelon help contribute to the important anti-inflammatory properties of this fruit.

The most abundant nutrients found within watermelon include vitamin C, pantothenic acid, copper, biotin, vitamin A, vitamin B1, and vitamin B6.

These nutrients and many more phytonutrients all contribute to the anti-inflammatory, antioxidant and cardiovascular benefits seen with watermelon consumption.

In one cup of watermelon:

  • Calories – there are approximately 45 calories. One serving of watermelon can be considered to be low-calorie.
  • Protein – there is approximately 1 gram of protein. Watermelon is not a significant source of protein in the diet.
  • Carbs – there are approximately 12 grams of carbohydrates (because there are 12 grams of carbohydrates and only 0.5 grams of dietary fiber, watermelon has approximately 11.5 grams of net carbohydrates. )
  • Fiber – there are approximately 0.5 grams of dietary fiber
  • Fat – there is approximately 0.25 grams of fat. Watermelon is not a significant source of fat in the diet.

Is Watermelon Paleo?

Yes, watermelon is paleo and can make be an excellent Paleo choice when enjoyed in moderation.

Watermelon is also Autoimmune Paleo Protocol friendly, and you can find a recipe for a delicious Watermelon & Arugula Salad inside my first cookbook, The 30-Minute Thyroid Cookbook: 125 Healing Recipes for Hypothyroidism & Hashimoto’s.

The Health Benefits of Apple Cider Vinegar

The second most important ingredient found in this delicious watermelon shooter is apple cider vinegar.

Many people in the wellness world are not new to taking a shot of apple cider vinegar for a variety of health reasons.

Many of the anecdotal reasons people say they consume apple cider vinegar include:

  • Improved digestion
  • Improved blood sugar control

This wellness trend is a personal preference, and I encourage you to try things out for yourself and decide what makes a good addition to your own personal routine.

Determine The Dose

Want to get a more accurate guesstimate of the potency of your cannabis infusions and extractions? Try my popular edibles dosage calculator. Not sure what your perfect dose is? Learn more here.

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More Delicious Drink Recipes

Find even more cannabis drink recipes here.

A picture of a shot glass with cannabis infused watermelon juice.

Cannabis Watermelon Shooter Shots

5 from 9 votes
Whether you’re starting your morning off right or planning a fun party or get-together, these cannabis-infused watermelon shooter shots are a nutrient-dense, quick and easy drink, complete with various cannabis infusion options.
Prep: 5 minutes
Total: 5 minutes
Servings: 4 (2 ounce) shots


  • 5 ounces watermelon puree
  • 2.5 ounces apple cider vinegar
  • 1 tablespoon honey
  • 1/16 teaspoon pumpkin pie spice
  • 1 mL cannabis alcohol tincture


  • In a blender, puree the watermelon and measure to 5 ounces.
  • Add the apple cider vinegar, honey, and pumpkin pie spice. Blend on high for 60-seconds.
  • Gently stir in the cannabis tincture, or oil, if using.
  • Garnish and enjoy.


Serving: 2ounces, Calories: 30kcal, Carbohydrates: 7g, Sodium: 1mg, Sugar: 7g

Additional Info

Course: Drinks
Cuisine: Cannabis Recipe
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About Emily

Hi, I’m Emily Kyle and I teach people just like you how to use cannabis to find joy, enhance productivity, improve relationships, and naturally support your overall health and wellness.

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