If you’re searching for natural, targeted relief from menstrual pain, endometriosis, or chronic pelvic discomfort, this article features step-by-step guide to making your own cannabis suppositories at home. You’ll learn why this method may be especially helpful for those who haven’t found relief with other approaches, and discover the reasons behind using FECO for maximum potency.

Table of Contents
Recipe Features
- Instructions for making cannabis suppositories at home for rectal or vaginal relief.
- An explanation of why FECO/RSO is the best choice for potency.
- Want to skip the hard work? Skip the lengthy infusion process, order my high-quality cannabis topical products, and have them delivered directly to your door!

Why You Will Love This Recipe
You might be exploring this recipe for the same reasons I did, searching for targeted relief from conditions like endometriosis, PID, painful periods, or other forms of pelvic pain. What you will find is an application method that offers a unique and powerful form of support.
Here’s why cannabis-infused suppositories are so special:
- Targeted Action: Unlike oral consumption, suppositories deliver cannabinoids directly to the dense network of receptors in the pelvic region, offering localized relief without a strong psychoactive high.
- Potency Control: By using a concentrated cannabis extract like FECO, you have complete control over the strength of each suppository.
- Minimal Ingredients: This recipe uses just two simple ingredients, ensuring you know exactly what you are putting into your body.
For me, making my own suppositories was an act of taking back control. It allowed me to create a solution tailored specifically to my body’s needs, using ingredients I trusted. It’s a profoundly personal and empowering process, and I can’t wait to share it with you.

DIY Cannabis Suppository Recipe for Relief
What You Need
- ¼ cup coconut oil (60mL)
- ¼ cup cacao butter (40g)
- 1 mL Full Extract Cannabis Oil (FECO) or Rick Simpson Oil (RSO)
Instructions
Prepare Your Infusion
- Make sure you have purchased or prepared your FECO/RSO ahead of time, as this concentrated cannabis extract is essential for potency and must be ready before starting. While using cannabis-infused coconut oil is possible in a pinch, please note the resulting suppositories will be far less potent and not as effective for targeted relief.
Prepare the Mix
- Set Up a Double Boiler: Fill a small saucepan with about an inch of water and bring it to a very gentle simmer. Place your small glass dish or beaker in the water.
- Melt the Carriers: Add ¼ cup coconut oil and ¼ cup cacao butter to the glass dish. Allow them to melt completely, stirring occasionally. Keep the heat very low to preserve the beneficial properties of both oils.
- Incorporate the FECO: Once the oils are fully melted, add 1 mL Full Extract Cannabis Oil (FECO) or Rick Simpson Oil (RSO) to the mixture. Stir gently but thoroughly until the thick, dark extract is fully dissolved and the blend is uniform. This may take a few minutes of gentle stirring.
- Fill the Mold: Carefully pour or spoon the warm liquid mixture into your suppository mold. If using a dropper, work quickly before the mixture begins to cool and solidify.
- Chill to Set: Place the filled mold in the refrigerator or freezer for at least one hour, or until the suppositories are completely firm. Once solid, gently pop them out of the mold and store as directed.
Notes
- Safety First: Always use food-grade, body-safe ingredients in this recipe. Avoid adding essential oils, fragrances, or any other substances that could be too strong, irritating, or unsafe for internal use. The sensitive mucosal tissues can react to additives, so stick to the basic recipe for gentle, effective relief.
- Molds: If you don’t have a dedicated suppository mold, you can find small, cylindrical silicone molds online intended for ice sticks or candy.
- Dosage: This recipe creates a batch. To calculate the dose per suppository, divide the total milligrams of cannabinoids in your 1mL of FECO by the number of suppositories your mold makes. For example, if your FECO has 700mg of THC and your mold makes 10 suppositories, each one will have approximately 70mg of THC.
- Application: For menstrual pain, using a suppository at the first sign of cramps can be most effective. They are best used when you can lie down for 15-20 minutes afterward to ensure they melt and are fully absorbed.

What You’ll Need
- Equipment:
- Small, heat-safe glass dish or beaker
- Small saucepan (for a double boiler)
- Suppository mold (silicone molds are widely available online)
- Small spatula or stirring rod
Ingredients:
- 1/4 cup (60ml) Coconut Oil: This acts as a nourishing, meltable base for the suppositories and helps with absorption.
- 1/4 cup (40g) Cacao Butter: This adds firmness and stability, ensuring the suppositories hold their shape at cooler temperatures.
- 1mL Full Extract Cannabis Oil (FECO) or Rick Simpson Oil (RSO): This concentrated cannabis extract provides the potency necessary for effective relief.

Step-by-Step Instructions
- Fill a small saucepan or a double boiler with about an inch of water and bring it to a very gentle simmer.
- Put the ¼ cup (60ml) coconut oil in a small glass dish or beaker and gently place that in the water.
- Add ¼ cup (40g) cacao butter to the glass dish.
- Allow them to melt completely, stirring occasionally. Keep the heat very low to preserve the beneficial properties of both oils.

- Once the oils are fully melted, add 1mL of FECO (or RSO) to the mixture. Stir gently but thoroughly until the thick, dark extract is fully dissolved and the blend is uniform. This may take a few minutes of gentle stirring.
- Carefully pour or spoon the warm liquid mixture into your suppository mold. If using a dropper, work quickly before the mixture begins to cool and solidify.
- Place the filled mold in the refrigerator or freezer for at least one hour, or until the suppositories are completely firm.
- Once solid, gently pop them out of the mold and store as directed.
Storage Instructions
Proper storage is crucial for maintaining the integrity and safety of your suppositories.
- Always store suppositories in the refrigerator. Coconut oil and cacao butter will melt at or near body temperature, so keeping them cold is essential for them to remain solid.
- Store them in a sealed, airtight container. Label the container clearly with the contents and date.
- When stored correctly in the refrigerator, your suppositories should last for several months.
SAVE THIS GUIDE 💌

Alternate Infusion Options
For many recipes, like edibles and topicals, you have a wide range of choices for your cannabis source. However, for suppositories, this is not the case.
When I first started, I tried making them with regular cannabis-infused coconut oil. The results were disappointing. I had to use a large amount of the infused oil to get any noticeable effect, which resulted in a messy, low-potency product.
Here is why FECO/RSO is the only truly viable infusion option for potent suppositories:
- Potency by Volume: Suppositories are small. You need to pack a significant therapeutic dose into a tiny volume. A gram of FECO can contain 600-900mg of cannabinoids. To get that same dose from a standard cannabis-infused coconut oil (made with 7 grams of flower per cup), you would need to use a massive, impractical amount of oil.
- Concentration is Key: FECO is a pure cannabis extract. By dissolving it into a small amount of carrier oil, you create a product where the cannabis is the star. With infused coconut oil, the oil itself is the main ingredient, and the cannabis is just along for the ride.
- Full Spectrum Benefits: FECO/RSO is a whole-plant extract, meaning it contains not just THC or CBD, but the full array of cannabinoids and terpenes from the original plant. This creates an “entourage effect,” where the compounds work together synergistically for a more powerful therapeutic outcome.
Simply put, using cannabis-infused oil would be like trying to make a strong cup of coffee with one used tea bag. You need the concentrated power of FECO to achieve the desired therapeutic effect.

Benefits of Cannabis Suppositories
The use of suppositories as a delivery method is not new; it has been used in medicine for centuries. Applying it to cannabis offers unique benefits that other consumption methods can’t match.
- High Bioavailability: The rectal and vaginal membranes are highly permeable and rich in blood vessels, allowing for efficient absorption of cannabinoids directly into the local tissues and bloodstream.
- Bypasses the Liver: When you eat an edible, the THC passes through your liver, where it is converted into a more potent psychoactive compound (11-hydroxy-THC). Suppositories largely bypass this “first-pass metabolism,” which is why they typically do not produce the intense, disorienting high associated with edibles.
- Localized Relief: For pelvic conditions, this is the biggest advantage. The cannabinoids are delivered right to the source of the pain and inflammation, providing targeted relief that can be more effective than systemic medications.
Notes and Expert Tips
- Molds: If you don’t have a dedicated suppository mold, you can find small, cylindrical silicone molds online intended for ice sticks or candy.
- Dosage: This recipe creates a batch. To calculate the dose per suppository, divide the total milligrams of cannabinoids in your gram of FECO by the number of suppositories your mold makes. For example, if your 1g of FECO has 700mg of THC and your mold makes 10 suppositories, each one will have approximately 70mg of THC.
- Application: For menstrual pain, using a suppository at the first sign of cramps can be most effective. They are best used when you can lie down for 15-20 minutes afterward to ensure they melt and are fully absorbed.
Will Cannabis Suppositories Get Me High?
This is the most common and important question. For most people, the answer is no, not in the traditional sense. Because the cannabinoids are absorbed locally and largely bypass the liver, you will not experience the strong psychoactive “head high” that you would from an edible.
However, you may feel a sense of deep body relaxation, a gentle “body buzz,” or a feeling of warmth and relief in the pelvic region. Everyone’s body is different, so it’s always wise to start with a lower dose and see how you feel. The goal here is therapeutic relief, not intoxication.
Conclusion
Making your own cannabis suppositories might seem a little scary at first, but you now have all the tools you need to create a gentle, natural option right at home. You are doing a wonderful job exploring new ways to care for your body.
Remember to start slow and listen to what your body tells you. Everyone responds differently to plant-based care. Finding your perfect balance is simply part of the process. You are in complete control of your ingredients and your dose, so take your time and figure out what feels best for you.
If you have any questions, need a little extra guidance, or just want to share how this recipe worked for you, please leave a comment below. Your stories inspire me and help others feel more confident, too. Keep nourishing yourself, and enjoy the soothing relief you truly deserve!

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